The highest dose used in the rat and mouse teratogenicity studies was equivalent to a clindamycin phosphate dose of 432 mg/kg. Antiperistaltic agents, such as opiates and diphenoxylate with atropine, may prolong and/or worsen the condition.Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of oral and parenteral therapy with clindamycinGeneral: Clindamycin Phosphate Topical Gel should be prescribed with caution in atopic individuals.Drug Interactions: Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.Safety and effectiveness in children under the age of 12 have not been established.The clinical study with Clindamycin Phosphate Topical Gel did not include sufficient numbers of patients aged 65 and over to determine if they respond differently than younger patients.In the one well-controlled clinical study comparing Clindamycin Phosphate Topical Gel and its vehicle, the incidence of skin and appendages adverse events occurring in ≥1% of the patients in either group is presented below:Orally and parenterally administered clindamycin has been associated with severe colitis, which may end fatally.Cases of diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see To report SUSPECTED ADVERSE REACTIONS, contact Valeant Pharmaceuticals North America LLC at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.Topically applied Clindamycin Phosphate Topical Gel may be absorbed in sufficient amounts to produce systemic effects (see WARNINGS).Apply a thin film of Clindamycin Phosphate Topical Gel once daily to the skin where acne lesions appear. For a rat, this dose is 84- fold higher and for a mouse, 42-fold higher than the anticipated human dose of clindamycin phosphate from Clindamycin Phosphate Topical Gelbased on a mg/mIt is not known whether clindamycin is excreted in human milk following use of Clindamycin Phosphate Topical Gel. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy. Chemically, clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chlorosubstitution of the 7 (R)-hydroxyl group of the parent antibiotic, lincomycin, and has the structural formula represented below: The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-Following multiple applications of Clindamycin Phosphate Topical Gel less than 0.04% of the total dose was excreted in the urine.In one 12-week multicenter, randomized, evaluator-blind, vehicle-controlled, parallel comparison clinical trial in which patients used Clindamycin Phosphate Topical Gel once daily or the vehicle gel once daily, in the treatment of acne vulgaris of mild to moderate severity, Clindamycin Phosphate Topical Gelapplied once daily was more effective than the vehicle applied once daily. ClearGel® Gel 20g/0.7oz Clindamycin Phosphate USP 1%. Clindamycin Phosphate Gel contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram. Prescription prices may vary from pharmacy to pharmacy and are subject to change. Select one or more newsletters to continue. Use of the topical formulation of clindamycin results in absorption of theantibiotic from the skin surface. Cinderella Myles price for clindamycin phosphate knit her metallic underdid justifiably?
Prices start at $9.93 Available for Android and iOS devices. Compare prices, print coupons and get savings tips for Clindamycin (Generic Cleocin T, Evoclin, and Cleocin) and other Skin Infection, Acne, Bacterial Infection, Upper Respiratory Infection, Lower Respiratory Infection, Pneumonia, and Bacterial Vaginosis drugs at CVS, Walgreens, and other pharmacies. The cost for clindamycin topical topical foam 1% is around $195 for a supply of 50 grams, depending on the pharmacy you visit.